STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_2064Arginase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR014033: IPR005924: IPR006035: IPR020855; KEGG: rxy:Rxyl_1270 arginase; PFAM: Arginase/agmatinase/formiminoglutamase; SPTR: Arginase; TIGRFAM: arginase; PFAM: Arginase family; TIGRFAM: arginase; Belongs to the arginase family. (303 aa)    
Predicted Functional Partners:
Tmar_0538
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
    
 0.914
argJ
N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
     
 0.912
Tmar_1347
Arginine decarboxylase; COGs: COG1945 conserved hypothetical protein; InterPro IPR002724: IPR000209; KEGG: swo:Swol_0667 pyruvoyl-dependent arginine decarboxylase; PFAM: Pyruvoyl-dependent arginine decarboxylase; PRIAM: Arginine decarboxylase; SPTR: Arginine decarboxylase; TIGRFAM: arginine decarboxylase, pyruvoyl-dependent; PFAM: Pyruvoyl-dependent arginine decarboxylase (PvlArgDC); TIGRFAM: arginine decarboxylase, pyruvoyl-dependent.
    
 0.908
Tmar_2342
Arginine decarboxylase; COGs: COG1945 conserved hypothetical protein; InterPro IPR002724; KEGG: tjr:TherJR_1055 arginine decarboxylase, pyruvoyl-dependent; PFAM: Pyruvoyl-dependent arginine decarboxylase; PRIAM: Arginine decarboxylase; SPTR: Arginine decarboxylase, pyruvoyl-dependent; TIGRFAM: arginine decarboxylase, pyruvoyl-dependent; PFAM: Pyruvoyl-dependent arginine decarboxylase (PvlArgDC); TIGRFAM: arginine decarboxylase, pyruvoyl-dependent.
    
 0.908
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
    
 0.876
argD
COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814: IPR004636; KEGG: bts:Btus_2268 acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Acetylornithine and succinylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
 
 0.843
argH
COGs: COG0165 Argininosuccinate lyase; InterPro IPR003031: IPR000362: IPR020557: IPR009049; KEGG: bts:Btus_2198 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
     
 0.817
argH-2
COGs: COG0165 Argininosuccinate lyase; InterPro IPR000362: IPR003031: IPR009049; KEGG: sth:STH2750 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
     
 0.817
Tmar_2332
COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814: IPR004632; KEGG: sth:STH616 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; PRIAM: (S)-3-amino-2-methylpropionate transaminase; SPTR: 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.776
Tmar_0154
Protein of unknown function DUF1385; COGs: COG3872 metal-dependent protein; InterPro IPR010787; KEGG: mta:Moth_2398 hypothetical protein; PFAM: protein of unknown function DUF1385; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1385).
   
    0.667
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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