STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_2331Transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR000485: IPR019888: IPR019887; KEGG: pab:PAB2257 transcriptional regulatory protein; PFAM: Transcription regulator AsnC-type-like; SMART: Transcription regulator AsnC-type; SPTR: Uncharacterized HTH-type transcriptional regulator PYRAB01370; PFAM: DeoR-like helix-turn-helix domain; AsnC family. (167 aa)    
Predicted Functional Partners:
Tmar_2332
COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814: IPR004632; KEGG: sth:STH616 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; PRIAM: (S)-3-amino-2-methylpropionate transaminase; SPTR: 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
   
 0.686
Tmar_2330
CutA1 divalent ion tolerance protein; COGs: COG1324 conserved hypothetical protein involved in tolerance to divalent cations; InterPro IPR004323; KEGG: adg:Adeg_0037 CutA1 divalent ion tolerance protein; PFAM: CutA1 divalent ion tolerance protein; SPTR: CutA1 divalent ion tolerance protein; PFAM: CutA1 divalent ion tolerance protein.
       0.615
Tmar_0631
Glutamate synthase (NADPH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: rrs:RoseRS_2985 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (NADH); SPTR: Glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.610
Tmar_1260
Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
  
 0.478
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
   
  
 0.420
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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