STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_0126NADH dehydrogenase (quinone); COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750; KEGG: rci:RCIX2384 hydrogenase, membrane subunit 1-like protein (EchA-like); PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: Hydrogenase, membrane subunit 1-like protein (EchA-like); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains. (486 aa)    
Predicted Functional Partners:
Sgly_0127
NADH dehydrogenase (ubiquinone) 30 kDa subunit; COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR001268: IPR001501: IPR001135; KEGG: dae:Dtox_0795 NADH dehydrogenase (ubiquinone) 30 kDa subunit; PFAM: NADH:ubiquinone oxidoreductase, 30kDa subunit; Nickel-dependent hydrogenase, large subunit; NADH-quinone oxidoreductase, subunit D; SPTR: Similar to membrane-bound [NiFe]-hydrogenase-3, large subunit (Chain E); PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase.
 
 0.997
Sgly_0128
NADH dehydrogenase (quinone); COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137; KEGG: cce:Ccel_1686 NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: Strongly similar to membrane-bound [NiFe]-hydrogenase-3, small subunit (Chain G); PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
 
 0.995
Sgly_0124
Respiratory-chain NADH dehydrogenase subunit 1; COGs: COG0650 Formate hydrogenlyase subunit 4; InterPro IPR001694; KEGG: nde:NIDE4264 putative formate hydrogenlyase, membrane subunit; PFAM: NADH:ubiquinone oxidoreductase, subunit 1; SPTR: Similar to membrane-bound [NiFe]-hydrogenase-3, subunit D; PFAM: NADH dehydrogenase.
 
 
 0.990
Sgly_0125
Hydrogenase, membrane subunit 2-like protein; COGs: COG4237 Hydrogenase 4 membrane component (E); KEGG: rci:RCIX2385 hydrogenase, membrane subunit 2-like protein; SPTR: Hydrogenase, membrane subunit 2-like protein.
 
  
 0.979
Sgly_2060
Ech hydrogenase subunit A; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR001750; KEGG: mem:Memar_0364 NADH dehydrogenase (quinone); PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: Ech hydrogenase subunit A; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus.
 
 
0.946
Sgly_2058
COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137; KEGG: mpi:Mpet_0467 NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH ubiquinone oxidoreductase, 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
 
 0.892
Sgly_2056
COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR001501: IPR001135; KEGG: cpy:Cphy_1734 NADH-ubiquinone oxidoreductase chain 49kDa; PFAM: NADH-quinone oxidoreductase, subunit D; Nickel-dependent hydrogenase, large subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-ubiquinone oxidoreductase chain 49kDa; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase.
 
 0.869
Sgly_2059
COGs: COG0650 Formate hydrogenlyase subunit 4; InterPro IPR001694; KEGG: mem:Memar_0363 respiratory-chain NADH dehydrogenase, subunit 1; PFAM: NADH:ubiquinone oxidoreductase, subunit 1; SPTR: Ech hydrogenase subunit B; PFAM: NADH dehydrogenase.
 
 0.849
Sgly_0123
NADH dehydrogenase (quinone); COGs: COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750; KEGG: nde:NIDE4265 formate hydrogenlyase, membrane subunit; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: Formate hydrogenlyase, membrane subunit; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains.
 
    
0.842
Sgly_0165
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880: IPR019752: IPR019456: IPR011766: IPR 011895; KEGG: dhd:Dhaf_0054 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate-flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavo [...]
  
 
 0.715
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.