STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_1093KEGG: mcc:705843 cholesterol 24-hydroxylase-like; SPTR: cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to Homo sapiens cholesterol 24-hydroxylase mRNA. (143 aa)    
Predicted Functional Partners:
Sgly_1092
Flagellar hook-associated 2 domain-containing protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
       0.746
Sgly_1091
COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR013384: IPR001492; KEGG: cth:Cthe_2242 flagellar hook-associated protein FlgL; PFAM: Flagellin, N-terminal; SPTR: Flagellar hook-associated protein 3; TIGRFAM: Flagellar hook-associated protein 3; PFAM: Bacterial flagellin N-terminal helical region; TIGRFAM: flagellar hook-associated protein 3.
       0.716
flgK-2
COGs: COG1256 Flagellar hook-associated protein; InterPro IPR002371: IPR001444: IPR010930; KEGG: cth:Cthe_2244 flagellar hook-associated protein FlgK; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal; SPTR: Flagellar hook-associated protein FlgK; TIGRFAM: Flagellar hook-associated protein, FlgK; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar hook-associated protein FlgK.
       0.687
flgK-3
COGs: COG1256 Flagellar hook-associated protein; InterPro IPR002371: IPR001444: IPR010930; KEGG: cth:Cthe_2243 flagellar hook-associated protein FlgK; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal; SPTR: Flagellar hook-associated protein FlgK; TIGRFAM: Flagellar hook-associated protein, FlgK; PFAM: Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK.
       0.687
Sgly_1088
Fagellar hook-basal body protein; COGs: COG1749 Flagellar hook protein FlgE; InterPro IPR020013: IPR001444: IPR011491: IPR010930; KEGG: cth:Cthe_0474 protein of unknown function DUF1078-like protein; PFAM: Flagellar basal body FlaE; Flagellar basal body rod protein, N-terminal; Protein of unknown function DUF1078, C-terminal; SPTR: Putative uncharacterized protein; TIGRFAM: Fagellar hook-basal body protein, FlgE/F/G; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; Flagellar basal body protein FlaE; TIGRFAM: fagellar hook-basal body proteins; flagellar basal [...]
       0.566
csrA-2
Carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
       0.516
Sgly_1087
Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.
       0.497
Sgly_1095
Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
       0.401
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.