STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_2331COGs: COG1564 Thiamine pyrophosphokinase; InterPro IPR007371: IPR006282; KEGG: dhd:Dhaf_3841 thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase, catalytic domain; SPTR: Thiamine pyrophosphokinase; TIGRFAM: Thiamin pyrophosphokinase; PFAM: Thiamin pyrophosphokinase, vitamin B1 binding domain; Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase. (219 aa)    
Predicted Functional Partners:
rsgA
Ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
  
 
 0.964
rsgA-2
Ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
  
 
 0.918
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.905
Sgly_0279
COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: afn:Acfer_1880 alkaline phosphatase; PFAM: Alkaline phosphatase; PRIAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; PFAM: Alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
  0.900
Sgly_2332
COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: dhd:Dhaf_3842 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Putative uncharacterized protein; TIGRFAM: Ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase.
 
  
 0.836
Sgly_0165
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880: IPR019752: IPR019456: IPR011766: IPR 011895; KEGG: dhd:Dhaf_0054 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate-flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavo [...]
   
   0.730
Sgly_2330
KEGG: aau:AAur_2195 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.723
Sgly_2341
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
   
 0.686
Sgly_2334
COGs: COG0515 Serine/threonine protein kinase; InterPro IPR017442: IPR005543: IPR020635: IPR002290; KEGG: dhd:Dhaf_3844 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA; PRIAM: Mitogen-activated protein kinase kinase kinase; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, catalytic domain; PASTA; SPTR: Putative uncharacterized protein; PFAM: Protein kinase domain; PASTA domain.
  
  
 0.665
Sgly_2337
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR014045: IPR001932; KEGG: dhd:Dhaf_3847 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C, N-terminal; SMART: Protein phosphatase 2C-related; SPTR: Putative uncharacterized protein; PFAM: Protein phosphatase 2C.
     
 0.581
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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