STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mus81Mus81. (844 aa)    
Predicted Functional Partners:
rqh1
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
 0.983
swi10
Swi10.
   
 0.981
Top3a
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.975
MEC1
MEC1; Belongs to the PI3/PI4-kinase family.
    
 0.941
NPL4
NPL4.
   
 0.936
RPL1
RPL1.
    
 0.925
EHP00_1750
Asparagine--tRNA.
  
 0.915
RAD51A
DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.
   
 0.912
pol
Pol.
    
  0.899
Tf2-6
Tf2-6.
    
  0.899
Your Current Organism:
Enterocytozoon hepatopenaei
NCBI taxonomy Id: 646526
Other names: E. hepatopenaei, Enterocytozoon sp. ST-2009a
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.