STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubiA4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (331 aa)    
Predicted Functional Partners:
Rvan_0311
KEGG: mch:Mchl_0014 glutaredoxin-like protein; TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily.
     0.923
Rvan_2292
PFAM: Polyprenyl synthetase; KEGG: bid:Bind_0855 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.905
Rvan_0758
PFAM: Endoribonuclease L-PSP; KEGG: acr:Acry_3477 endoribonuclease L-PSP.
    
  0.904
Rvan_1004
KEGG: rce:RC1_2080 geranylgeranyl reductase BchP; TIGRFAM: geranylgeranyl reductase; PFAM: FAD dependent oxidoreductase.
  
 
 0.842
Rvan_1734
PFAM: inositol monophosphatase; KEGG: inositol monophosphatase.
     
 0.800
ubiG
Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 
 0.772
Rvan_0535
Von Willebrand factor type A; KEGG: rce:RC1_2082 magnesium chelatase subunit D; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A.
  
  
 0.698
Rvan_1732
Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
 
    0.690
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
     
 0.623
Rvan_1602
Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone.
 
  
 0.620
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.