STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU96912.1Ribonuclease HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (270 aa)    
Predicted Functional Partners:
ADU96913.1
PFAM: protein of unknown function DUF490; KEGG: sul:SYO3AOP1_1462 hypothetical protein.
 
     0.816
ADU96911.1
KEGG: pca:Pcar_1881 signal peptide peptidase SppA, 67K type; TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: peptidase S49.
       0.786
ADU96914.1
Hypothetical protein; KEGG: kko:Kkor_0901 TPR repeat-containing protein.
       0.786
ADU96915.1
PFAM: histidine triad (HIT) protein; KEGG: tpe:Tpen_0562 histidine triad (HIT) protein.
       0.786
ADU96910.1
PFAM: Lytic transglycosylase catalytic; KEGG: dsh:Dshi_1605 lytic murein transglycosylase.
       0.784
purD
KEGG: tjr:TherJR_0831 phosphoribosylamine/glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family.
       0.763
ADU96916.1
Hypothetical protein; KEGG: dac:Daci_4054 alanyl-tRNA synthetase.
       0.741
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
      
 0.642
ADU96917.1
PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: pmx:PERMA_0865 phage integrase family protein; Belongs to the 'phage' integrase family.
  
    0.561
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
      
 0.482
Your Current Organism:
Thermovibrio ammonificans
NCBI taxonomy Id: 648996
Other names: T. ammonificans HB-1, Thermovibrio ammonificans DSM 15698, Thermovibrio ammonificans HB-1, Thermovibrio ammonificans str. HB-1, Thermovibrio ammonificans strain HB-1
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