STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_0114DNA-N1-methyladenine dioxygenase; COGs: COG3145 Alkylated DNA repair protein; InterPro IPR005123; KEGG: phe:Phep_1031 2OG-Fe(II) oxygenase; PFAM: 2OG-Fe(II) oxygenase; SPTR: Alkylated DNA repair protein; PFAM: 2OG-Fe(II) oxygenase superfamily. (200 aa)    
Predicted Functional Partners:
Lbys_1995
Ketopantoate reductase ApbA/PanE domain protein; COGs: COG1893 Ketopantoate reductase; InterPro IPR013332:IPR013752; KEGG: sli:Slin_2608 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein; SPTR: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase.
   
    0.761
Lbys_0113
DNA-O6-methylguanine--protein-cysteine S-methyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR001497:IPR014048:IPR000005:IPR018060; KEGG: fjo:Fjoh_1575 methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: DNA-O6-methylguanine--protein-cysteine S-methyltransferase / Transcriptional regulator Ada; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguani [...]
  
 0.745
Lbys_0110
Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198:IPR002347; KEGG: acd:AOLE_00935 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
      0.437
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
Server load: medium (80%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.