STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_0218COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160:IPR015590:IPR011408; KEGG: fba:FIC_01836 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (780 aa)    
Predicted Functional Partners:
Lbys_0219
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.
 
 0.980
Lbys_3134
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 0.932
Lbys_2891
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR016160:IPR012394; KEGG: lic:LIC12761 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Putative uncharacterized protein; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.923
Lbys_0017
Methylmalonate-semialdehyde dehydrogenase (acylating); COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160:IPR010061:IPR015590; KEGG: dfe:Dfer_5699 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase.
  
  
 
0.921
Lbys_0249
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: dfe:Dfer_5034 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family.
  
  
 
0.915
Lbys_1257
Succinate CoA transferase; COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702:IPR017821; KEGG: bba:Bd1620 acetyl-CoA hydrolase/transferase family protein; PFAM: acetyl-CoA hydrolase/transferase; PRIAM: Acetyl-CoA hydrolase; SPTR: Acetyl-CoA hydrolase/transferase family protein; TIGRFAM: succinate CoA transferase; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; Citrate lyase, alpha subunit (CitF); TIGRFAM: succinate CoA transferases.
  
 
 0.907
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
     
 0.902
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
    
 0.901
Lbys_3086
COGs: COG1929 Glycerate kinase; InterPro IPR004381; KEGG: ccv:CCV52592_0612 glycerate kinase 1; PFAM: glycerate kinase; PRIAM: Glycerate kinase; SPTR: Glycerate kinase 1; TIGRFAM: glycerate kinase; PFAM: Glycerate kinase family; TIGRFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family.
   
 
 0.901
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
     
 0.900
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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