STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Trad_1633COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR019818:IPR001804:IPR014273; KEGG: gwc:GWCH70_0444 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: A3UKF0 Isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase; isocitrate dehydrogenase, NADP-dependent, prokaryotic type. (492 aa)    
Predicted Functional Partners:
Trad_0147
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.941
Trad_0897
COGs: COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1); InterPro IPR011603:IPR001017:IPR005475; KEGG: hoh:Hoch_4994 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; PRIAM: Oxoglutarate dehydrogenase (succinyl-transferring); SPTR: B9XMW8 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component.
  
 0.917
argH
COGs: COG0165 Argininosuccinate lyase; InterProIPR003031:IPR000362:IPR020557:IPR008948:IPR 009049; KEGG: dge:Dgeo_2065 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: D0T647 Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; manually curated; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
  
 
 0.834
Trad_0120
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR016161:IPR016162:IPR016160; KEGG: sth:STH722 succinate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Q67RI6 Succinate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.824
Trad_0137
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR016161:IPR016162:IPR016160; KEGG: rmr:Rmar_2008 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: D0MKH7 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family.
  
 0.824
Trad_2971
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838:IPR015421:IPR004839:IPR015424; KEGG: dra:DR_0623 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Q9RWP3 Aspartate aminotransferase; PFAM: Aminotransferase class I and II.
  
 
 0.812
Trad_2452
COGs: COG0015 Adenylosuccinate lyase; InterProIPR000362:IPR019468:IPR003031:IPR020557:IPR 008948:IPR004769; KEGG: dge:Dgeo_0688 adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; SPTR: Q1J0J4 Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
  0.805
Trad_0386
COGs: COG2902 NAD-specific glutamate dehydrogenase; InterPro IPR020539:IPR007780:IPR016040; KEGG: rxy:Rxyl_2529 glutamate dehydrogenase (NAD); PFAM: NAD-glutamate dehydrogenase; SPTR: Q1AT32 Glutamate dehydrogenase (NAD); PFAM: Bacterial NAD-glutamate dehydrogenase.
     
  0.800
leuC
Homoaconitate hydratase family protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 0.789
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
  
 0.762
Your Current Organism:
Truepera radiovictrix
NCBI taxonomy Id: 649638
Other names: T. radiovictrix DSM 17093, Truepera radiovictrix DSM 17093, Truepera radiovictrix RQ-24, Truepera radiovictrix str. DSM 17093, Truepera radiovictrix strain DSM 17093
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