STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
Trad_2471Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068:IPR010916:IPR008978; KEGG: ttj:TTHA1484 hsp 20 family small heat shock protein; PFAM: heat shock protein Hsp20; SPTR: B7ABU5 Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. (154 aa)    
Predicted Functional Partners:
Trad_2953
Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068:IPR008978; KEGG: ttj:TTHA0571 small heat shock protein; PFAM: heat shock protein Hsp20; SPTR: Q72L60 Probable small heat shock protein; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family.
  
     0.773
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.644
Trad_0082
Clp domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterPro IPR004176; KEGG: dge:Dgeo_1215 ATPase AAA-2; PFAM: Clp domain protein; SPTR: Q1IZ22 ATPase AAA-2; PFAM: Clp amino terminal domain.
  
 
 0.641
Trad_2216
ATPase AAA-2 domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR001270:IPR003593:IPR004176:IPR003959:IPR 013093:IPR019489:IPR018368; KEGG: ttj:TTHA0542 ATP-dependent Clp protease, ATP-binding subunit (ClpA); PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: Q72L86 ATP-dependent clp protease ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cel [...]
  
 
 0.641
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.547
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.440
Trad_2073
20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
  
 0.413
Trad_2470
KEGG: predicted protein; SPTR: C0GUV7 Putative uncharacterized protein.
       0.408
Trad_2472
InterPro IPR000620; KEGG: ttj:TTHA0205 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: C1XX57 Integral membrane protein DUF6; PFAM: EamA-like transporter family.
       0.401
Your Current Organism:
Truepera radiovictrix
NCBI taxonomy Id: 649638
Other names: T. radiovictrix DSM 17093, Truepera radiovictrix DSM 17093, Truepera radiovictrix RQ-24, Truepera radiovictrix str. DSM 17093, Truepera radiovictrix strain DSM 17093
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.