STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)    
Predicted Functional Partners:
ADU31466.1
KEGG: pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family.
 
 
 0.992
pgi
KEGG: bpf:BpOF4_04585 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
 0.967
ADU32331.1
TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; KEGG: bha:BH3786 fructose-1,6-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II.
 
 
 0.954
ADU28834.1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.915
ADU30653.1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.915
ADU31837.1
TIGRFAM: mannose-6-phosphate isomerase, class I; KEGG: oih:OB2765 mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type I; Belongs to the mannose-6-phosphate isomerase type 1 family.
    
 0.915
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
   
  
 0.914
ADU30018.1
PFAM: PfkB domain protein; KEGG: carbohydrate kinase family protein.
  
 
 0.908
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
  
 
0.902
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.779
Your Current Organism:
Bacillus cellulosilyticus
NCBI taxonomy Id: 649639
Other names: B. cellulosilyticus DSM 2522, Bacillus cellulosilyticus DSM 2522, Bacillus cellulosilyticus str. DSM 2522, Bacillus cellulosilyticus strain DSM 2522, Bacillus sp. (STRAIN N-4), Bacillus sp. ATCC 21833, Bacillus sp. N-4
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