node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEI38778.1 | SEI51446.1 | SAMN05421831_101185 | SAMN05421831_103123 | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | 0.955 |
SEI38778.1 | SEI55401.1 | SAMN05421831_101185 | SAMN05421831_10467 | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Oxaloacetate decarboxylase, alpha subunit. | 0.962 |
SEI38778.1 | SEI87786.1 | SAMN05421831_101185 | SAMN05421831_1153 | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Acetolactate synthase, small subunit. | 0.929 |
SEI38778.1 | SEI87808.1 | SAMN05421831_101185 | SAMN05421831_1154 | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Acetolactate synthase, large subunit. | 0.936 |
SEI38778.1 | leuC | SAMN05421831_101185 | SAMN05421831_1214 | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.930 |
SEI38778.1 | leuD | SAMN05421831_101185 | SAMN05421831_1215 | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.932 |
SEI51446.1 | SEI38778.1 | SAMN05421831_103123 | SAMN05421831_101185 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.955 |
SEI51446.1 | SEI55401.1 | SAMN05421831_103123 | SAMN05421831_10467 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | Oxaloacetate decarboxylase, alpha subunit. | 0.957 |
SEI51446.1 | SEI87786.1 | SAMN05421831_103123 | SAMN05421831_1153 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | Acetolactate synthase, small subunit. | 0.934 |
SEI51446.1 | SEI87808.1 | SAMN05421831_103123 | SAMN05421831_1154 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | Acetolactate synthase, large subunit. | 0.962 |
SEI51446.1 | ilvD | SAMN05421831_103123 | SAMN05421831_110110 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.599 |
SEI51446.1 | leuB | SAMN05421831_103123 | SAMN05421831_1216 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.501 |
SEI51446.1 | leuC | SAMN05421831_103123 | SAMN05421831_1214 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.934 |
SEI51446.1 | leuD | SAMN05421831_103123 | SAMN05421831_1215 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.937 |
SEI55401.1 | SEI38778.1 | SAMN05421831_10467 | SAMN05421831_101185 | Oxaloacetate decarboxylase, alpha subunit. | Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.962 |
SEI55401.1 | SEI51446.1 | SAMN05421831_10467 | SAMN05421831_103123 | Oxaloacetate decarboxylase, alpha subunit. | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). | 0.957 |
SEI55401.1 | SEI87786.1 | SAMN05421831_10467 | SAMN05421831_1153 | Oxaloacetate decarboxylase, alpha subunit. | Acetolactate synthase, small subunit. | 0.930 |
SEI55401.1 | SEI87808.1 | SAMN05421831_10467 | SAMN05421831_1154 | Oxaloacetate decarboxylase, alpha subunit. | Acetolactate synthase, large subunit. | 0.936 |
SEI55401.1 | ilvC | SAMN05421831_10467 | SAMN05421831_1152 | Oxaloacetate decarboxylase, alpha subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.462 |
SEI55401.1 | leuC | SAMN05421831_10467 | SAMN05421831_1214 | Oxaloacetate decarboxylase, alpha subunit. | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.933 |