STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2C9JD62DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (569 aa)    
Predicted Functional Partners:
A0A2C9JFR1
AP_endonuc_2 domain-containing protein.
    
 0.977
A0A2C9LK23
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
  
  
 0.949
A0A2C9KVM9
Endo/exonuclease/phosphatase domain-containing protein.
  
 
 0.948
A0A2C9JNN8
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
  
  
0.921
A0A2C9JFU8
Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
  
 0.846
A0A2C9KGG5
Uncharacterized protein.
  
 0.835
A0A2C9KFC3
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.813
A0A2C9L9G8
Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.789
A0A2C9JGB0
Small nuclear ribonucleoprotein Sm D3.
   
 0.764
A0A2C9K4U8
ENDO3c domain-containing protein.
  
 0.761
Your Current Organism:
Biomphalaria glabrata
NCBI taxonomy Id: 6526
Other names: Australorbis glabratus, B. glabrata, Planorbis glabratus, bloodfluke planorb
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