STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH11716.1Aspartate transaminase; KEGG: fra:Francci3_0064 aminotransferase AlaT; PFAM: Aminotransferase, class I/II. (423 aa)    
Predicted Functional Partners:
ilvD
PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; HAMAP: Dihydroxy-acid dehydratase; KEGG: fre:Franean1_7305 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
   
 
 0.911
AEH10150.1
KEGG: fre:Franean1_1935 glutamate synthase (ferredoxin); PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal.
    
 0.908
AEH07849.1
KEGG: fre:Franean1_7207 Glu/Leu/Phe/Val dehydrogenase dimerisation region; PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region; Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.907
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
     
 0.903
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.903
AEH11018.1
TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase related; KEGG: fra:Francci3_3628 putative alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
 
 0.900
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
   
 
 0.900
AEH08494.1
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component; KEGG: fre:Franean1_0984 alpha-ketoglutarate decarboxylase; PFAM: Transketolase-like, pyrimidine-binding domain; Dehydrogenase, E1 component; 2-oxoacid dehydrogenase acyltransferase, catalytic domain.
   
 0.867
AEH11265.1
TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: fal:FRAAL1051 putative oxidoreductase,alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal.
    
 0.855
AEH08115.1
Aspartate kinase; KEGG: fre:Franean1_6573 aspartate kinase; TIGRFAM: Aspartate kinase region; Aspartate kinase, monofunctional class; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; Belongs to the aspartokinase family.
  
 0.853
Your Current Organism:
Frankia symbiont
NCBI taxonomy Id: 656024
Other names: F. symbiont of Datisca glomerata, Frankia symbiont of Datisca glomerata
Server load: low (24%) [HD]