STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)    
Predicted Functional Partners:
gltA
Citrate synthase; Equals llo1803; Belongs to the citrate synthase family.
  
 0.979
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.969
capP
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.932
LLO_3348
Equals llo3348; similar to aspartate aminotransferase.
  
 0.926
sfcA
Malate dehydrogenase, (decarboxylating, NAD-requiring) (malic enzyme); Equals llo0429.
  
 0.925
LLO_0659
Putative NADP-dependent malic enzyme; Equals llo0659.
  
 0.925
sfcA-2
Malate oxidoreductase; Equals llo1147.
  
 0.925
LLO_2561
Equals llo2561; similar to NADP-dependent malic enzyme.
  
 0.925
aspB
Equals llo1324; similar to aspartate aminotransferase.
  
 0.921
prpC
2-methylcitrate synthase; Equals llo1556; Belongs to the citrate synthase family.
  
 0.896
Your Current Organism:
Legionella longbeachae
NCBI taxonomy Id: 661367
Other names: L. longbeachae NSW150, Legionella longbeachae NSW150, Legionella longbeachae str. NSW150, Legionella longbeachae strain NSW150
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