STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARB_05408DNA ligase. (844 aa)    
Predicted Functional Partners:
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.932
ARB_04898
DNA ligase.
  
  
 
0.908
ARB_06134
Vezatin domain-containing protein.
   
 0.894
ARB_06135
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.894
POL3
DNA polymerase.
   
 0.860
ARB_00500
Replication factor C subunit.
   
 0.855
ARB_01174
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.822
ARB_06958
MCM domain-containing protein; Belongs to the MCM family.
   
  
 0.781
ARB_04765
Replication factor C subunit 1.
   
 0.764
ARB_04766
AAA domain-containing protein.
   
 0.763
Your Current Organism:
Trichophyton benhamiae
NCBI taxonomy Id: 663331
Other names: Arthroderma benhamiae CBS 112371, T. benhamiae CBS 112371, Trichophyton benhamiae CBS 112371
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.