node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGK51809.1 | tmk | B1NLA3E_00125 | B1NLA3E_00130 | Orn/Lys/Arg decarboxylase major region; COG1982 Arginine/lysine/ornithine decarboxylases. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.732 |
AGK52078.1 | AGK53584.1 | B1NLA3E_01470 | B1NLA3E_09110 | Stationary-phase survival protein SurE; COG0496 Predicted acid phosphatase. | 5'-nucleotidase domain-containing protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.911 |
AGK52078.1 | AGK54992.1 | B1NLA3E_01470 | B1NLA3E_16240 | Stationary-phase survival protein SurE; COG0496 Predicted acid phosphatase. | Cytidine deaminase ComEB; COG2131 Deoxycytidylate deaminase. | 0.900 |
AGK52078.1 | AGK55490.1 | B1NLA3E_01470 | B1NLA3E_18730 | Stationary-phase survival protein SurE; COG0496 Predicted acid phosphatase. | Metallophosphoesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.911 |
AGK52078.1 | dut | B1NLA3E_01470 | B1NLA3E_17060 | Stationary-phase survival protein SurE; COG0496 Predicted acid phosphatase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.903 |
AGK52078.1 | tdk | B1NLA3E_01470 | B1NLA3E_21580 | Stationary-phase survival protein SurE; COG0496 Predicted acid phosphatase. | COG1435 Thymidine kinase. | 0.921 |
AGK52078.1 | thyA | B1NLA3E_01470 | B1NLA3E_14235 | Stationary-phase survival protein SurE; COG0496 Predicted acid phosphatase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.920 |
AGK52078.1 | tmk | B1NLA3E_01470 | B1NLA3E_00130 | Stationary-phase survival protein SurE; COG0496 Predicted acid phosphatase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.914 |
AGK53584.1 | AGK52078.1 | B1NLA3E_09110 | B1NLA3E_01470 | 5'-nucleotidase domain-containing protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Stationary-phase survival protein SurE; COG0496 Predicted acid phosphatase. | 0.911 |
AGK53584.1 | AGK54992.1 | B1NLA3E_09110 | B1NLA3E_16240 | 5'-nucleotidase domain-containing protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Cytidine deaminase ComEB; COG2131 Deoxycytidylate deaminase. | 0.903 |
AGK53584.1 | AGK55490.1 | B1NLA3E_09110 | B1NLA3E_18730 | 5'-nucleotidase domain-containing protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Metallophosphoesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.919 |
AGK53584.1 | dut | B1NLA3E_09110 | B1NLA3E_17060 | 5'-nucleotidase domain-containing protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
AGK53584.1 | tdk | B1NLA3E_09110 | B1NLA3E_21580 | 5'-nucleotidase domain-containing protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | COG1435 Thymidine kinase. | 0.920 |
AGK53584.1 | thyA | B1NLA3E_09110 | B1NLA3E_14235 | 5'-nucleotidase domain-containing protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.904 |
AGK53584.1 | tmk | B1NLA3E_09110 | B1NLA3E_00130 | 5'-nucleotidase domain-containing protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.924 |
AGK54869.1 | dut | B1NLA3E_15615 | B1NLA3E_17060 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.838 |
AGK54869.1 | ndk | B1NLA3E_15615 | B1NLA3E_14800 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.920 |
AGK54869.1 | tdk | B1NLA3E_15615 | B1NLA3E_21580 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | COG1435 Thymidine kinase. | 0.445 |
AGK54869.1 | thyA | B1NLA3E_15615 | B1NLA3E_14235 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.855 |
AGK54869.1 | tmk | B1NLA3E_15615 | B1NLA3E_00130 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.943 |