STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E9GML8_DAPPUGuanylate cyclase domain-containing protein. (630 aa)    
Predicted Functional Partners:
E9FT53_DAPPU
Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
0.942
E9HUQ2_DAPPU
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.902
E9GNM3_DAPPU
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
 0.901
Punch
Putative GTP cyclohydrolase I protein punch.
     
 0.800
E9GYN4_DAPPU
Uncharacterized protein.
   
 0.726
E9GYN5_DAPPU
PDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family.
   
 0.726
E9FYU8_DAPPU
Phosphodiesterase.
   
 0.721
E9FT33_DAPPU
Phosphodiesterase.
   
 0.718
E9FX16_DAPPU
Phosphodiesterase.
   
 0.718
E9GD11_DAPPU
Phosphodiesterase.
   
 0.718
Your Current Organism:
Daphnia pulex
NCBI taxonomy Id: 6669
Other names: D. pulex, common water flea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.