STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EQB71256.1Hypothetical protein; S4JAPL_C00031G00027; S4JAPL_17500G0027; Belongs to the peptidase S16 family. (658 aa)    
Predicted Functional Partners:
EQB71257.1
Hypothetical protein; S4JAPL_C00031G00028; S4JAPL_17500G0028.
       0.773
eno
Hypothetical protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.752
grpE
Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...]
  
  
 0.750
dnaK
Hypothetical protein; Acts as a chaperone.
 
  
 0.719
rpl40e
50S ribosomal protein L40E; S4JAPL_C00001G00032; S4JAPL_13214G0032; Belongs to the eukaryotic ribosomal protein eL40 family.
  
  
  0.692
EQB72596.1
Hypothetical protein; S4JAPL_C00006G00020; S4JAPL_13186G0020.
  
     0.632
rlmE
FtsJ-like protein methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
  
   0.612
EQB71258.1
Hypothetical protein; S4JAPL_C00031G00029; S4JAPL_17500G0029.
 
     0.610
EQB67794.1
Thermosome, alpha chain; S4JAPL_C00095G00003; S4JAPL_11661G0003.
 
 
 0.609
EQB71676.1
Hypothetical protein; S4JAPL_C00020G00042; S4JAPL_17357G0042.
  
     0.597
Your Current Organism:
Thermoplasmatales archaeon Aplasma
NCBI taxonomy Id: 667135
Other names: T. archaeon A-plasma, Thermoplasmatales archaeon A-plasma
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.