STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crsACeramide synthase. (257 aa)    
Predicted Functional Partners:
dcd3B
Alkaline dihydroceramidase.
    
 0.932
PPL_10160
acidPPc domain-containing protein.
    
 0.930
ksrA-2
3-dehydrosphinganine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.899
PPL_00357
Uncharacterized protein.
     
 0.869
sgkA
Sphingosine kinase.
     
 0.863
sgmB
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family.
     
 0.861
sgmA
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family.
     
 0.861
desA
Sphingolipid delta 4 desaturase.
    
 0.855
PPL_10738
Putative sphingomyelinase.
     
 0.851
dcd3A
Alkaline dihydroceramidase.
    
 0.800
Your Current Organism:
Heterostelium album
NCBI taxonomy Id: 670386
Other names: H. album PN500, Heterostelium album PN500, Heterostelium pallidum PN500, Polysphondylium pallidum PN500
Server load: low (26%) [HD]