STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bzpRPutative basic-leucine zipper transcription factor. (656 aa)    
Predicted Functional Partners:
PPL_06934
DHR10 domain-containing protein.
   
 0.828
ndc80
Kinetochore protein Ndc80.
    
 0.778
PPL_02081
RING zinc finger-containing protein.
    
 0.764
erkA
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.764
erkB
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.764
bub1
Uncharacterized protein.
    
  0.665
PPL_02403
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.645
PPL_06444
WD40 repeat-containing protein.
   
 0.645
H4a
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.631
PPL_08539
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.631
Your Current Organism:
Heterostelium album
NCBI taxonomy Id: 670386
Other names: H. album PN500, Heterostelium album PN500, Heterostelium pallidum PN500, Polysphondylium pallidum PN500
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.