STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR37285.1Phosphate ABC transporter membrane protein 2, PhoT family; COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515: IPR005672; KEGG: mrb:Mrub_2520 phosphate ABC transporter inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter, inner membrane subunit PstA; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA. (275 aa)    
Predicted Functional Partners:
pstB
Phosphate ABC transporter ATP-binding protein, PhoT family; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
 0.999
ADR37286.1
Phosphate ABC transporter membrane protein 1, PhoT family; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
0.999
ADR37287.1
Phosphate ABC transporter substrate-binding protein, PhoT family; COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR005673: IPR006059; KEGG: mrb:Mrub_2518 phosphate ABC transporter periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Phosphate ABC transporter, periplasmic phosphate-binding protein; TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: phosphate ABC transporter, phosphate-binding protein; Belongs to the PstS [...]
 
 0.998
ADR37288.1
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
  
 0.988
ADR37283.1
COGs: COG2062 Phosphohistidine phosphatase SixA; InterPro IPR013078; KEGG: aeh:Mlg_1872 phosphohistidine phosphatase, SixA; PFAM: Phosphoglycerate mutase; SPTR: Phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase family; TIGRFAM: phosphohistidine phosphatase SixA.
       0.784
ADR37289.1
Histidine kinase; COGs: COG5002 Signal transduction histidine kinase; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: mrb:Mrub_1540 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
     
 0.548
ADR37290.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: msv:Mesil_0841 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
     
 0.513
ADR37291.1
Hypothetical protein; KEGG: lch:Lcho_2109 ABC-type phosphate/phosphonate transport system periplasmic component-like protein; SPTR: ABC-type phosphate/phosphonate transport system periplasmic component.
  
  
 0.511
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.494
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR002547: IPR005146: IPR005147: IPR005121: IPR 004532; KEGG: mrb:Mrub_2673 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spiroch [...]
  
  
 0.483
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
Server load: high (86%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.