STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR37635.1COGs: COG1850 Ribulose 1 5-bisphosphate carboxylase large subunit; InterPro IPR000685; KEGG: tle:Tlet_1684 ribulose-bisphosphate carboxylase; PFAM: ribulose bisphosphate carboxylase large chain; SPTR: RubisCO-like protein; PFAM: Ribulose bisphosphate carboxylase large chain, catalytic domain. (384 aa)    
Predicted Functional Partners:
ADR35715.1
HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG0546 phosphatase; InterPro IPR005834: IPR006402: IPR006439; KEGG: mxa:MXAN_6112 HAD family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 [...]
    
 0.914
ADR37637.1
Transketolase domain-containing protein; COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: tle:Tlet_1682 transketolase domain-containing protein; PFAM: Transketolase domain-containing protein; SPTR: Transketolase domain protein; PFAM: Transketolase, thiamine diphosphate binding domain.
 
     0.891
ADR37636.1
Transketolase central region; COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR005475: IPR005476; KEGG: tle:Tlet_1683 transketolase central region; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: Transketolase central region; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
 
     0.875
ADR37634.1
Transcriptional regulator, DeoR family; COGs: COG2390 Transcriptional regulator contains sigma factor-related N-terminal domain; InterPro IPR007324; KEGG: tle:Tlet_1685 DeoR family transcriptional regulator; PFAM: sugar-binding domain-containing protein; SPTR: Transcriptional regulator, DeoR family; PFAM: Sigma-70, region 4; Putative sugar-binding domain.
 
     0.845
mtnK-2
5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
 
  
 0.803
mtnA-2
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
 
  
 0.772
mtnK
5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
 
  
 0.576
pgk
COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR015911: IPR001576; KEGG: tth:TTC0550 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
 0.573
ADR36901.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  
 0.537
ADR37351.1
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR017936: IPR017937: IPR005746: IPR013766: IPR 006662; KEGG: msv:Mesil_3022 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
    
 
 0.523
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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