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dtd protein (Vibrio vulnificus) - STRING interaction network
"dtd" - D-aminoacyl-tRNA deacylase in Vibrio vulnificus
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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dtdD-aminoacyl-tRNA deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl- tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality; Belongs to the DTD family (144 aa)    
Predicted Functional Partners:
VV0205
annotation not available (308 aa)
 
   
  0.909
rbn
annotation not available (313 aa)
   
        0.895
VV0202
annotation not available (213 aa)
              0.659
lpxH
UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (243 aa)
         
  0.554
VV2359
annotation not available (682 aa)
 
     
  0.531
VV2279
annotation not available (126 aa)
           
  0.531
cca
Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3’- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2’- nucleotidase and 2’,3’-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3’-CCA terminus degraded by intracellular RNases (436 aa)
 
 
      0.513
hisI
annotation not available (211 aa)
              0.467
VV1185
annotation not available (138 aa)
         
  0.461
tyrA
annotation not available (375 aa)
              0.457
Your Current Organism:
Vibrio vulnificus
NCBI taxonomy Id: 672
Other names: ATCC 27562, BCRC 12905, Beneckea vulnifica, CAIM 610, CCRC 12905, CCUG 13448, CCUG 16394, CIP 75.4, DSM 10143, IFO 15645, JCM 3725, LMG 13545, NBRC 15645, V. vulnificus, Vibrio vulnificus, strain 324
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