| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| VV0686 | VV2979 | VV93_v1c06260 | VV93_v1c27080 | annotation not available | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | 0.445 |
| VV0686 | ileS | VV93_v1c06260 | VV93_v1c06270 | annotation not available | Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily | 0.956 |
| VV0686 | lspA | VV93_v1c06260 | VV93_v1c06280 | annotation not available | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family | 0.737 |
| VV0686 | murJ | VV93_v1c06260 | VV93_v1c06250 | annotation not available | Probable lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane | 0.881 |
| VV0686 | rpsT | VV93_v1c06260 | VV93_v1c06240 | annotation not available | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA | 0.635 |
| VV2979 | VV0686 | VV93_v1c27080 | VV93_v1c06260 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | annotation not available | 0.445 |
| VV2979 | ftsW | VV93_v1c27080 | VV93_v1c05560 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | Probable peptidoglycan glycosyltransferase FtsW; Peptidoglycan polymerase that is essential for cell division; Belongs to the SEDS family. FtsW subfamily | 0.531 |
| VV2979 | murJ | VV93_v1c27080 | VV93_v1c06250 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | Probable lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane | 0.762 |
| cysS | ileS | VV93_v1c12750 | VV93_v1c06270 | annotation not available | Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily | 0.850 |
| cysS | murJ | VV93_v1c12750 | VV93_v1c06250 | annotation not available | Probable lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane | 0.672 |
| ftsW | VV2979 | VV93_v1c05560 | VV93_v1c27080 | Probable peptidoglycan glycosyltransferase FtsW; Peptidoglycan polymerase that is essential for cell division; Belongs to the SEDS family. FtsW subfamily | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins | 0.531 |
| ftsW | lspA | VV93_v1c05560 | VV93_v1c06280 | Probable peptidoglycan glycosyltransferase FtsW; Peptidoglycan polymerase that is essential for cell division; Belongs to the SEDS family. FtsW subfamily | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family | 0.582 |
| ftsW | mrdA | VV93_v1c05560 | VV93_v1c08430 | Probable peptidoglycan glycosyltransferase FtsW; Peptidoglycan polymerase that is essential for cell division; Belongs to the SEDS family. FtsW subfamily | Peptidoglycan D,D-transpeptidase MrdA; Catalyzes cross-linking of the peptidoglycan cell wall; Belongs to the transpeptidase family. MrdA subfamily | 0.783 |
| ftsW | murJ | VV93_v1c05560 | VV93_v1c06250 | Probable peptidoglycan glycosyltransferase FtsW; Peptidoglycan polymerase that is essential for cell division; Belongs to the SEDS family. FtsW subfamily | Probable lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane | 0.635 |
| glnD | murJ | VV93_v1c22780 | VV93_v1c06250 | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...] | Probable lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane | 0.646 |
| ileS | VV0686 | VV93_v1c06270 | VV93_v1c06260 | Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily | annotation not available | 0.956 |
| ileS | cysS | VV93_v1c06270 | VV93_v1c12750 | Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily | annotation not available | 0.850 |
| ileS | lspA | VV93_v1c06270 | VV93_v1c06280 | Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family | 0.965 |
| ileS | murJ | VV93_v1c06270 | VV93_v1c06250 | Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily | Probable lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane | 0.680 |
| ileS | rpsT | VV93_v1c06270 | VV93_v1c06240 | Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA | 0.534 |
