mrdA protein (Vibrio vulnificus) - STRING interaction network

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mrdA

Peptidoglycan D,D-transpeptidase MrdA; Catalyzes cross-linking of the peptidoglycan cell wall; Belongs to the transpeptidase family. MrdA subfamily (630 aa)

Predicted Functional Partners:

rodA

0.998

rlmH

0.970

mreC

0.950

mreB

0.948

rlpA

0.932

VV0902

0.899

ftsI

0.895

VV0903

0.857

rsfS

0.839

VV2756

0.829

Your Current Organism:

Vibrio vulnificus

NCBI taxonomy Id: 672
Other names: ATCC 27562, BCRC 12905, Beneckea vulnifica, CAIM 610, CCRC 12905, CCUG 13448, CCUG 16394, CIP 75.4, DSM 10143, IFO 15645, JCM 3725, LMG 13545, NBRC 15645, V. vulnificus, Vibrio vulnificus, strain 324

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
VV0902	VV0903	VV93_v1c08390	VV93_v1c08400	annotation not available	annotation not available	0.760
VV0902	mrdA	VV93_v1c08390	VV93_v1c08430	annotation not available	Peptidoglycan D,D-transpeptidase MrdA; Catalyzes cross-linking of the peptidoglycan cell wall; Belongs to the transpeptidase family. MrdA subfamily	0.899
VV0902	mreB	VV93_v1c08390	VV93_v1c26570	annotation not available	annotation not available	0.530
VV0902	rlmH	VV93_v1c08390	VV93_v1c08440	annotation not available	Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family	0.524
VV0902	rlpA	VV93_v1c08390	VV93_v1c08410	annotation not available	Endolytic peptidoglycan transglycosylase RlpA; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	0.582
VV0902	rodA	VV93_v1c08390	VV93_v1c08420	annotation not available	Peptidoglycan glycosyltransferase MrdB; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily	0.893
VV0902	rsfS	VV93_v1c08390	VV93_v1c08450	annotation not available	Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	0.494
VV0903	VV0902	VV93_v1c08400	VV93_v1c08390	annotation not available	annotation not available	0.760
VV0903	ftsI	VV93_v1c08400	VV93_v1c05510	annotation not available	Peptidoglycan D,D-transpeptidase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily	0.400
VV0903	mrdA	VV93_v1c08400	VV93_v1c08430	annotation not available	Peptidoglycan D,D-transpeptidase MrdA; Catalyzes cross-linking of the peptidoglycan cell wall; Belongs to the transpeptidase family. MrdA subfamily	0.857
VV0903	mreC	VV93_v1c08400	VV93_v1c26560	annotation not available	Cell shape-determining protein MreC; Involved in formation and maintenance of cell shape	0.417
VV0903	rlmH	VV93_v1c08400	VV93_v1c08440	annotation not available	Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family	0.594
VV0903	rlpA	VV93_v1c08400	VV93_v1c08410	annotation not available	Endolytic peptidoglycan transglycosylase RlpA; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	0.665
VV0903	rodA	VV93_v1c08400	VV93_v1c08420	annotation not available	Peptidoglycan glycosyltransferase MrdB; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily	0.841
VV0903	rsfS	VV93_v1c08400	VV93_v1c08450	annotation not available	Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	0.526
VV2756	ftsI	VV93_v1c24680	VV93_v1c05510	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	Peptidoglycan D,D-transpeptidase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily	0.831
VV2756	mrdA	VV93_v1c24680	VV93_v1c08430	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	Peptidoglycan D,D-transpeptidase MrdA; Catalyzes cross-linking of the peptidoglycan cell wall; Belongs to the transpeptidase family. MrdA subfamily	0.829
VV2756	mreB	VV93_v1c24680	VV93_v1c26570	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	annotation not available	0.420
VV2756	mreC	VV93_v1c24680	VV93_v1c26560	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	Cell shape-determining protein MreC; Involved in formation and maintenance of cell shape	0.516
VV2756	rodA	VV93_v1c24680	VV93_v1c08420	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	Peptidoglycan glycosyltransferase MrdB; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily	0.721

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