Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Fusion
Genes that are sometimes fused into single open reading frames.
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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VV1009
annotation not available (530 aa)
Predicted Functional Partners:
VV2526
annotation not available
0.652
kefB
Glutathione-regulated potassium-efflux system protein KefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1
node2
node1 accession
node2 accession
node1 annotation
node2 annotation
score
VV1009
VV1010
VV93_v1c09320
VV93_v1c09330
annotation not available
annotation not available
0.613
VV1009
VV2526
VV93_v1c09320
VV93_v1c22470
annotation not available
annotation not available
0.652
VV1009
VVA0010
VV93_v1c09320
VV93_v1c30210
annotation not available
annotation not available
0.483
VV1009
asnB
VV93_v1c09320
VV93_v1c09310
annotation not available
annotation not available
0.480
VV1009
kefB
VV93_v1c09320
VV93_v1c27710
annotation not available
Glutathione-regulated potassium-efflux system protein KefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport
0.648
VV1009
nagA
VV93_v1c09320
VV93_v1c09340
annotation not available
annotation not available
0.621
VV1010
VV1009
VV93_v1c09330
VV93_v1c09320
annotation not available
annotation not available
0.613
VV1010
asnB
VV93_v1c09330
VV93_v1c09310
annotation not available
annotation not available
0.410
VV1010
nagA
VV93_v1c09330
VV93_v1c09340
annotation not available
annotation not available
0.939
VV2526
VV1009
VV93_v1c22470
VV93_v1c09320
annotation not available
annotation not available
0.652
VVA0010
VV1009
VV93_v1c30210
VV93_v1c09320
annotation not available
annotation not available
0.483
asnB
VV1009
VV93_v1c09310
VV93_v1c09320
annotation not available
annotation not available
0.480
asnB
VV1010
VV93_v1c09310
VV93_v1c09330
annotation not available
annotation not available
0.410
kefB
VV1009
VV93_v1c27710
VV93_v1c09320
Glutathione-regulated potassium-efflux system protein KefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport
annotation not available
0.648
nagA
VV1009
VV93_v1c09340
VV93_v1c09320
annotation not available
annotation not available
0.621
nagA
VV1010
VV93_v1c09340
VV93_v1c09330
annotation not available
annotation not available
0.939
Network Stats
Network Stats analysis is still ongoing, please wait ...
Functional enrichments in your networkNote: some enrichments may be expected here (why?) explain columns
Enrichment analysis is still ongoing, please wait ...
Statistical background
For the above enrichment analysis, the following statistical background is assumed: