STRINGSTRING
luxU protein (Vibrio vulnificus) - STRING interaction network
"luxU" - Phosphorelay protein LuxU in Vibrio vulnificus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
luxUPhosphorelay protein LuxU; Phosphorelay protein which receives a sensory signal from a sensor kinase and transmit it to LuxO. At low cell density, a phosphoryl group is transferred from the sensor kinase, probably on His-56 and this phosphoryl group is further transferred to LuxO (115 aa)    
Predicted Functional Partners:
hydG
Regulatory protein LuxO; Involved in the regulation of different processes depending on the cell density. Acts together with sigma-54 to repress, perhaps indirectly, some genes (By similarity) (466 aa)
 
 
  0.989
luxP
Autoinducer 2-binding periplasmic protein LuxP; Binds to an autoinducer molecule. This complex then interacts with the LuxQ sensor protein (By similarity) (366 aa)
   
   
  0.971
luxQ
Autoinducer 2 sensor kinase/phosphatase LuxQ; At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to LuxU, and ultimately to LuxO. At high cell density, in the presence of autoinducer, the kinase activity is inactivated, and the response regulator domain has a phosphatase activity (By similarity) (857 aa)
 
  0.942
VV2733
annotation not available (1129 aa)
 
 
  0.855
VVA0933
annotation not available (1370 aa)
   
 
  0.814
VV0886
annotation not available (754 aa)
   
 
 
  0.786
VVA0786
annotation not available (124 aa)
   
          0.784
VVA0415
annotation not available (199 aa)
 
          0.783
VV0233
annotation not available (156 aa)
   
          0.782
VV0023
annotation not available (86 aa)
   
          0.781
Your Current Organism:
Vibrio vulnificus
NCBI taxonomy Id: 672
Other names: ATCC 27562, BCRC 12905, Beneckea vulnifica, CAIM 610, CCRC 12905, CCUG 13448, CCUG 16394, CIP 75.4, DSM 10143, IFO 15645, JCM 3725, LMG 13545, NBRC 15645, V. vulnificus, Vibrio vulnificus, strain 324
Server load: low (11%) [HD]