node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VV0634 | VV1263 | VV93_v1c05740 | VV93_v1c11810 | annotation not available | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | 0.986 |
VV0634 | VV1477 | VV93_v1c05740 | VV93_v1c13870 | annotation not available | annotation not available | 0.610 |
VV0634 | btuB | VV93_v1c05740 | VV93_v1c01540 | annotation not available | Vitamin B12 transporter BtuB; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB | 0.423 |
VV0634 | btuF | VV93_v1c05740 | VV93_v1c05730 | annotation not available | Vitamin B12-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC | 0.932 |
VV0634 | cobQ | VV93_v1c05740 | VV93_v1c38310 | annotation not available | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation | 0.993 |
VV0634 | cobS | VV93_v1c05740 | VV93_v1c13850 | annotation not available | Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate; Belongs to the CobS family | 0.863 |
VV0634 | cobT | VV93_v1c05740 | VV93_v1c13840 | annotation not available | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) | 0.910 |
VV0634 | cobU | VV93_v1c05740 | VV93_v1c13860 | annotation not available | Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family | 0.990 |
VV0634 | metH | VV93_v1c05740 | VV93_v1c26820 | annotation not available | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity) | 0.630 |
VV1263 | VV0634 | VV93_v1c11810 | VV93_v1c05740 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | annotation not available | 0.986 |
VV1263 | VV1264 | VV93_v1c11810 | VV93_v1c11820 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | annotation not available | 0.602 |
VV1263 | VV1477 | VV93_v1c11810 | VV93_v1c13870 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | annotation not available | 0.620 |
VV1263 | btuB | VV93_v1c11810 | VV93_v1c01540 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | Vitamin B12 transporter BtuB; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB | 0.649 |
VV1263 | btuF | VV93_v1c11810 | VV93_v1c05730 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | Vitamin B12-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC | 0.597 |
VV1263 | cobQ | VV93_v1c11810 | VV93_v1c38310 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation | 0.998 |
VV1263 | cobS | VV93_v1c11810 | VV93_v1c13850 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate; Belongs to the CobS family | 0.983 |
VV1263 | cobT | VV93_v1c11810 | VV93_v1c13840 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) | 0.876 |
VV1263 | cobU | VV93_v1c11810 | VV93_v1c13860 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | Bifunctional adenosylcobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate; Belongs to the CobU/CobP family | 0.989 |
VV1263 | metH | VV93_v1c11810 | VV93_v1c26820 | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity) | 0.819 |
VV1264 | VV1263 | VV93_v1c11820 | VV93_v1c11810 | annotation not available | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | 0.602 |