Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VV1486
annotation not available (76 aa)
Predicted Functional Partners:
VV0998
annotation not available
0.608
VV0105
annotation not available
0.606
rlmF
Ribosomal RNA large subunit methyltransferase F; Specifically methylates the adenine in position 1618 of 23S rRNA
0.603
VV2968
annotation not available
0.601
VV2565
annotation not available
0.593
VV1487
annotation not available
0.591
VV1244
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1
node2
node1 accession
node2 accession
node1 annotation
node2 annotation
score
VV0104
VV0105
VV93_v1c00940
VV93_v1c00950
annotation not available
annotation not available
0.882
VV0104
VV0998
VV93_v1c00940
VV93_v1c09230
annotation not available
annotation not available
0.780
VV0104
VV1443
VV93_v1c00940
VV93_v1c13550
annotation not available
annotation not available
0.776
VV0104
VV1486
VV93_v1c00940
VV93_v1c13960
annotation not available
annotation not available
0.514
VV0104
VV2565
VV93_v1c00940
VV93_v1c22850
annotation not available
annotation not available
0.781
VV0104
VV2968
VV93_v1c00940
VV93_v1c26980
annotation not available
annotation not available
0.736
VV0105
VV0104
VV93_v1c00950
VV93_v1c00940
annotation not available
annotation not available
0.882
VV0105
VV0998
VV93_v1c00950
VV93_v1c09230
annotation not available
annotation not available
0.780
VV0105
VV1443
VV93_v1c00950
VV93_v1c13550
annotation not available
annotation not available
0.781
VV0105
VV1486
VV93_v1c00950
VV93_v1c13960
annotation not available
annotation not available
0.606
VV0105
VV2565
VV93_v1c00950
VV93_v1c22850
annotation not available
annotation not available
0.783
VV0105
VV2968
VV93_v1c00950
VV93_v1c26980
annotation not available
annotation not available
0.758
VV0998
VV0104
VV93_v1c09230
VV93_v1c00940
annotation not available
annotation not available
0.780
VV0998
VV0105
VV93_v1c09230
VV93_v1c00950
annotation not available
annotation not available
0.780
VV0998
VV1443
VV93_v1c09230
VV93_v1c13550
annotation not available
annotation not available
0.775
VV0998
VV1486
VV93_v1c09230
VV93_v1c13960
annotation not available
annotation not available
0.608
VV0998
VV2565
VV93_v1c09230
VV93_v1c22850
annotation not available
annotation not available
0.782
VV0998
VV2968
VV93_v1c09230
VV93_v1c26980
annotation not available
annotation not available
0.761
VV1244
VV1486
VV93_v1c11640
VV93_v1c13960
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
annotation not available
0.568
VV1443
VV0104
VV93_v1c13550
VV93_v1c00940
annotation not available
annotation not available
0.776
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Network Stats
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Functional enrichments in your networkNote: some enrichments may be expected here (why?) explain columns
Enrichment analysis is still ongoing, please wait ...
Statistical background
For the above enrichment analysis, the following statistical background is assumed: