STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
luxQSignal transduction histidine kinase; At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to LuxU, and ultimately to LuxO. At high cell density, in the presence of autoinducer, the kinase activity is inactivated, and the response regulator domain has a phosphatase activity (By similarity). (857 aa)    
Predicted Functional Partners:
luxP
Sugar ABC transporter substrate-binding protein; Binds to an autoinducer molecule. This complex then interacts with the LuxQ sensor protein (By similarity); Belongs to the bacterial solute-binding protein 2 family.
   
 0.998
AIL73423.1
Sensory box sensor histidine kinase/response regulator.
 
 
0.988
AIL73376.1
Signal transduction histidine kinase.
 
 
0.986
luxU
Phosphorelay protein; Phosphorelay protein which receives a sensory signal from a sensor kinase and transmit it to LuxO. At low cell density, a phosphoryl group is transferred from the sensor kinase, probably on His-56 and this phosphoryl group is further transferred to LuxO.
  
 0.985
AIL72930.1
Signal transduction histidine kinase.
 
 
0.984
AIL69680.1
Aerobic respiration control sensor protein ArcB.
 
 
0.982
AIL72647.1
Two-component system sensor protein.
 
 
0.981
AIL69679.1
Sensory box/GGDEF family protein.
 
 
 0.973
AIL72377.1
Sensor kinase VieS.
 
 
0.971
AIL72704.1
Signal transduction histidine kinase.
 
 
0.971
Your Current Organism:
Vibrio vulnificus
NCBI taxonomy Id: 672
Other names: ATCC 27562, BCRC 12905, Beneckea vulnifica, CAIM 610, CCRC 12905, CCRC:12905, CCUG 13448, CCUG 16394, CIP 75.4, CIP:75.04, DSM 10143, IFO 15645, JCM 3725, LMG 13545, LMG:13545, NBRC 15645, NCIMB 2046, NCTC 13647, V. vulnificus, strain 324
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