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prfC protein (Pseudonocardia dioxanivorans) - STRING interaction network
"prfC" - Peptide chain release factor 3 in Pseudonocardia dioxanivorans
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (538 aa)    
Predicted Functional Partners:
Psed_1955
Glutamate synthase (1522 aa)
           
  0.612
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a "tag peptide", a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (161 aa)
     
      0.562
Psed_2944
Pyruvate, water dikinase (887 aa)
         
  0.529
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis (80 aa)
         
  0.470
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (366 aa)
     
 
  0.462
Psed_3432
Fmu (Sun) domain-containing protein (482 aa)
 
        0.451
Psed_3588
DNA polymerase I (939 aa)
         
  0.447
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (526 aa)
   
   
  0.447
Psed_5276
citryl-CoA lyase (266 aa)
         
  0.434
Psed_4168
citryl-CoA lyase (282 aa)
         
  0.434
Your Current Organism:
Pseudonocardia dioxanivorans
NCBI taxonomy Id: 675635
Other names: Actinobispora, Amycolata, P. dioxanivorans, P. dioxanivorans CB1190, Pseudamycolata, Pseudoamycolata, Pseudonocardia, Pseudonocardia dioxanivorans, Pseudonocardia dioxanivorans CB1190, Pseudonocardia dioxanivorans DSM 44775, Pseudonocardia dioxanivorans Mahendra and Alvarez-Cohen 2005, Pseudonocardia dioxanivorans str. CB1190, Pseudonocardia dioxanivorans strain CB1190
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