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Psed_3305 protein (Pseudonocardia dioxanivorans) - STRING interaction network
"Psed_3305" - Ubiquitin-like protein pup in Pseudonocardia dioxanivorans
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Psed_3305Ubiquitin-like protein pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (65 aa)    
Predicted Functional Partners:
Psed_3319
Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a ’key in a lock’ to induce gate opening and therefore regulate proteolysis (604 aa)
 
 
      0.925
Psed_3306
Proteasome accessory factor PafA2 (499 aa)
 
          0.876
prcA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (267 aa)
 
        0.852
prcB
Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (287 aa)
 
        0.843
pafA
Proteasome accessory factor PafA; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (453 aa)
 
          0.823
Psed_5089
Hypothetical protein (189 aa)
   
          0.580
Psed_0209
Hypothetical protein (184 aa)
   
        0.563
Psed_3290
Transcriptional regulator protein (346 aa)
 
          0.562
Psed_6548
Microtubule-severing ATPase (403 aa)
     
      0.550
Psed_6251
CbbX protein (342 aa)
     
      0.550
Your Current Organism:
Pseudonocardia dioxanivorans
NCBI taxonomy Id: 675635
Other names: Actinobispora, Amycolata, P. dioxanivorans, P. dioxanivorans CB1190, Pseudamycolata, Pseudoamycolata, Pseudonocardia, Pseudonocardia dioxanivorans, Pseudonocardia dioxanivorans CB1190, Pseudonocardia dioxanivorans DSM 44775, Pseudonocardia dioxanivorans Mahendra and Alvarez-Cohen 2005, Pseudonocardia dioxanivorans str. CB1190, Pseudonocardia dioxanivorans strain CB1190
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