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egtA protein (Pseudonocardia dioxanivorans) - STRING interaction network
"egtA" - Glutamate/cysteine ligase protein in Pseudonocardia dioxanivorans
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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egtAGlutamate/cysteine ligase protein; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine (455 aa)    
Predicted Functional Partners:
egtB
Hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine (468 aa)
 
   
  0.986
egtC
Hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine (271 aa)
 
   
  0.974
egtD
Methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine (330 aa)
 
   
  0.971
pepA
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (501 aa)
     
 
    0.905
Psed_6469
Hydantoinase/oxoprolinase (521 aa)
     
 
  0.904
Psed_6337
5-oxoprolinase (706 aa)
     
 
  0.904
Psed_6336
5-oxoprolinase (771 aa)
     
 
  0.904
Psed_5913
5-oxoprolinase (739 aa)
     
 
  0.904
Psed_5911
Hydantoinase/oxoprolinase (627 aa)
     
 
  0.904
Psed_5504
5-oxoprolinase (695 aa)
     
 
  0.904
Your Current Organism:
Pseudonocardia dioxanivorans
NCBI taxonomy Id: 675635
Other names: Actinobispora, Amycolata, P. dioxanivorans, P. dioxanivorans CB1190, Pseudamycolata, Pseudoamycolata, Pseudonocardia, Pseudonocardia dioxanivorans, Pseudonocardia dioxanivorans CB1190, Pseudonocardia dioxanivorans DSM 44775, Pseudonocardia dioxanivorans Mahendra and Alvarez-Cohen 2005, Pseudonocardia dioxanivorans str. CB1190, Pseudonocardia dioxanivorans strain CB1190
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