STRINGSTRING
rutA protein (Pseudonocardia dioxanivorans) - STRING interaction network
"rutA" - Pyrimidine utilization protein A in Pseudonocardia dioxanivorans
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rutAPyrimidine utilization protein A; Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (350 aa)    
Predicted Functional Partners:
psuG
Pseudouridine-5’-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5’- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway (309 aa)
       
    0.901
Psed_5383
Cytosine deaminase (427 aa)
         
    0.900
Psed_5291
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (207 aa)
         
    0.900
Psed_5287
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (268 aa)
         
    0.900
pyrR
Bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (195 aa)
         
    0.900
Psed_6203
Luciferase-like protein (349 aa)
              0.867
Psed_6204
MmgE/PrpD family protein (464 aa)
              0.859
Psed_6207
butyryl-CoA dehydrogenase (387 aa)
              0.816
Psed_6205
Amidase (474 aa)
              0.815
Psed_6208
formyl-CoA transferase (406 aa)
              0.815
Your Current Organism:
Pseudonocardia dioxanivorans
NCBI taxonomy Id: 675635
Other names: Actinobispora, Amycolata, P. dioxanivorans, P. dioxanivorans CB1190, Pseudamycolata, Pseudoamycolata, Pseudonocardia, Pseudonocardia dioxanivorans, Pseudonocardia dioxanivorans CB1190, Pseudonocardia dioxanivorans DSM 44775, Pseudonocardia dioxanivorans Mahendra and Alvarez-Cohen 2005, Pseudonocardia dioxanivorans str. CB1190, Pseudonocardia dioxanivorans strain CB1190
Server load: low (10%) [HD]