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prfC protein (Prevotella amnii) - STRING interaction network
"prfC" - Peptide chain release factor 3 in Prevotella amnii
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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prfCPeptide chain release factor 3 ; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (522 aa)    
Predicted Functional Partners:
rfbD
dTDP-4-dehydrorhamnose reductase (289 aa)
   
        0.628
guaA
Glutamine amidotransferase ; Catalyzes the synthesis of GMP from XMP (514 aa)
 
   
  0.615
HMPREF9018_0016
Uncharacterized protein (203 aa)
              0.596
polA
DNA-directed DNA polymerase (945 aa)
 
     
  0.592
HMPREF9018_0017
Translocator protein, LysE family (224 aa)
              0.533
smpB
Small protein B ; Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a "tag peptide", a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to tra [...] (159 aa)
     
      0.488
prfA
Peptide chain release factor 1 ; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (370 aa)
     
 
  0.455
pheT
Phenylalanyl-tRNA synthetase beta subunit (822 aa)
   
   
  0.453
guaB
Inosine-5’-monophosphate dehydrogenase (494 aa)
   
   
  0.411
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 679191
Other names: P. amnii, P. amnii CRIS 21A-A, Prevotella amnii, Prevotella amnii CRIS 21A-A, Prevotella amnii Lawson et al. 2008, Prevotella amnii str. CRIS 21A-A, Prevotella amnii strain CRIS 21A-A
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