STRINGSTRING
tsaD protein (Prevotella amnii) - STRING interaction network
"tsaD" - tRNA threonylcarbamoyladenosine biosynthesis protein TsaD in Prevotella amnii
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tsaDtRNA threonylcarbamoyladenosine biosynthesis protein TsaD ; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction (352 aa)    
Predicted Functional Partners:
yeaZ
Universal bacterial protein YeaZ (230 aa)
   
  0.976
HMPREF9018_0962
Hydrolase, P-loop family (136 aa)
 
  0.963
map
Peptidase M ; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (287 aa)
 
   
  0.887
secA
Protein translocase subunit SecA ; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (1117 aa)
 
   
  0.827
crcB
Putative fluoride ion transporter CrcB ; Important for reducing fluoride concentration in the cell, thus reducing its toxicity (125 aa)
     
      0.826
serS
Serine--tRNA ligase (429 aa)
 
 
  0.810
polA
DNA-directed DNA polymerase (945 aa)
 
   
  0.791
HMPREF9018_1577
ABC transporter, ATP-binding protein (241 aa)
 
        0.787
pheT
Phenylalanyl-tRNA synthetase beta subunit (822 aa)
   
   
  0.782
ksgA
S-adenosylmethionine-6-N’, N’-adenosyl(rRNA) dimethyltransferase ; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (267 aa)
 
   
  0.754
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 679191
Other names: P. amnii, P. amnii CRIS 21A-A, Prevotella amnii, Prevotella amnii CRIS 21A-A, Prevotella amnii Lawson et al. 2008, Prevotella amnii str. CRIS 21A-A, Prevotella amnii strain CRIS 21A-A
Server load: low (11%) [HD]