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HMPREF9018_0349 protein (Prevotella amnii) - STRING interaction network
"HMPREF9018_0349" - DNA gyrase/topoisomerase IV, A subunit in Prevotella amnii
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMPREF9018_0349DNA gyrase/topoisomerase IV, A subunit (905 aa)    
Predicted Functional Partners:
HMPREF9018_1028
DNA topoisomerase (ATP-hydrolyzing) (646 aa)
 
  0.995
gyrB
DNA gyrase subunit B ; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (656 aa)
  0.994
dnaN
DNA polymerase III subunit beta ; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (374 aa)
 
  0.925
HMPREF9018_0351
Peptidase, S41 family (334 aa)
              0.801
HMPREF9018_0350
Uncharacterized protein (258 aa)
              0.790
metG
Methionyl-tRNA synthetase ; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (687 aa)
   
 
  0.785
HMPREF9018_1111
Uncharacterized protein (432 aa)
   
          0.758
guaA
Glutamine amidotransferase ; Catalyzes the synthesis of GMP from XMP (514 aa)
     
   
  0.754
polA
DNA-directed DNA polymerase (945 aa)
   
 
  0.745
HMPREF9018_1725
Ribonucleoside-diphosphate reductase ; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (839 aa)
   
   
  0.716
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 679191
Other names: P. amnii, P. amnii CRIS 21A-A, Prevotella amnii, Prevotella amnii CRIS 21A-A, Prevotella amnii Lawson et al. 2008, Prevotella amnii str. CRIS 21A-A, Prevotella amnii strain CRIS 21A-A
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