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infB protein (Prevotella amnii) - STRING interaction network
"infB" - Translation initiation factor IF-2 in Prevotella amnii
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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infBTranslation initiation factor IF-2 ; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (966 aa)    
Predicted Functional Partners:
rpsB
30S ribosomal protein S2 (266 aa)
 
  0.987
infA
Translation initiation factor IF-1 ; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex (72 aa)
   
  0.985
rpsC
30S ribosomal protein S3 ; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (245 aa)
     
  0.972
rpsE
30S ribosomal protein S5 ; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (170 aa)
     
  0.970
rpsM
30S ribosomal protein S13 ; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P- sites (126 aa)
     
  0.962
infC
Translation initiation factor IF-3 ; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (227 aa)
   
  0.948
rpsP
30S ribosomal protein S16 (171 aa)
 
  0.946
rpsS
30S ribosomal protein S19 ; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (88 aa)
     
  0.946
rpsJ
30S ribosomal protein S10 ; Involved in the binding of tRNA to the ribosomes (101 aa)
     
  0.937
nusA
Transcription termination/antitermination protein NusA ; Participates in both transcription termination and antitermination (421 aa)
   
 
  0.933
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 679191
Other names: P. amnii, P. amnii CRIS 21A-A, Prevotella amnii, Prevotella amnii CRIS 21A-A, Prevotella amnii Lawson et al. 2008, Prevotella amnii str. CRIS 21A-A, Prevotella amnii strain CRIS 21A-A
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