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glyA protein (Prevotella amnii) - STRING interaction network
"glyA" - Serine hydroxymethyltransferase in Prevotella amnii
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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glyASerine hydroxymethyltransferase ; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (426 aa)    
Predicted Functional Partners:
HMPREF9018_1569
MGS-like domain protein (197 aa)
   
  0.981
rpiB
Ribose-5-phosphate isomerase B (146 aa)
   
      0.968
HMPREF9018_1515
AICARFT/IMPCHase bienzyme (393 aa)
   
  0.963
folD
Bifunctional protein FolD ; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (294 aa)
   
  0.962
HMPREF9018_0993
Uncharacterized protein (387 aa)
   
 
  0.921
fhs
Formyltetrahydrofolate synthetase (555 aa)
   
  0.919
HMPREF9018_0221
Phosphoribosylglycinamide synthetase (422 aa)
   
 
  0.915
purL
Formylglycinamide ribonucleotide amidotransferase ; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1247 aa)
   
   
  0.909
folC
Bifunctional protein FolC (436 aa)
   
  0.893
HMPREF9018_0790
L-serine ammonia-lyase (402 aa)
   
 
  0.886
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 679191
Other names: P. amnii, P. amnii CRIS 21A-A, Prevotella amnii, Prevotella amnii CRIS 21A-A, Prevotella amnii Lawson et al. 2008, Prevotella amnii str. CRIS 21A-A, Prevotella amnii strain CRIS 21A-A
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