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lepA protein (Prevotella amnii) - STRING interaction network
"lepA" - Ribosomal back-translocase LepA in Prevotella amnii
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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lepARibosomal back-translocase LepA ; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (593 aa)    
Predicted Functional Partners:
prfA
Peptide chain release factor 1 ; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (370 aa)
 
   
  0.771
pheS
Phenylalanyl-tRNA synthetase alpha subunit (346 aa)
   
   
  0.759
HMPREF9018_0849
Cyclic nucleotide-binding domain protein (199 aa)
              0.748
rplM
50S ribosomal protein L13 ; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (154 aa)
 
 
  0.703
pheT
Phenylalanyl-tRNA synthetase beta subunit (822 aa)
   
   
  0.689
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (387 aa)
 
   
  0.673
gidA
Glucose-inhibited division protein A ; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (631 aa)
 
   
  0.672
obg
GTP-binding protein Obg ; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control (388 aa)
 
   
  0.671
alaS
Alanyl-tRNA synthetase ; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (884 aa)
 
   
  0.666
aspS
Aspartate--tRNA ligase (585 aa)
 
   
  0.662
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 679191
Other names: P. amnii, P. amnii CRIS 21A-A, Prevotella amnii, Prevotella amnii CRIS 21A-A, Prevotella amnii Lawson et al. 2008, Prevotella amnii str. CRIS 21A-A, Prevotella amnii strain CRIS 21A-A
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