Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Transcriptional regulator, LuxR family (200 aa)
Predicted Functional Partners:
Hemerythrin HHE cation binding domain protein (318 aa)
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (471 aa)
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (456 aa)
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (520 aa)
DNA-directed DNA polymerase (945 aa)
Transcriptional regulator, LacI family (354 aa)
Excinuclease ABC subunit C ; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5’ and 3’ sides of the lesion. The N-terminal half is responsible for the 3’ incision and the C-terminal half is responsible for the 5’ incision (613 aa)