STRINGSTRING
HMPREF9018_1028 protein (Prevotella amnii) - STRING interaction network
"HMPREF9018_1028" - DNA topoisomerase in Prevotella amnii
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second shell of interactors
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filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMPREF9018_1028DNA topoisomerase (ATP-hydrolyzing) (646 aa)    
Predicted Functional Partners:
HMPREF9018_0349
DNA gyrase/topoisomerase IV, A subunit (905 aa)
 
  0.995
gyrA
DNA gyrase subunit A ; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (854 aa)
  0.995
dnaN
DNA polymerase III subunit beta ; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (374 aa)
 
  0.904
HMPREF9018_1027
Uncharacterized protein (382 aa)
              0.755
polA
DNA-directed DNA polymerase (945 aa)
   
 
  0.741
secA
Protein translocase subunit SecA ; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (1117 aa)
   
 
  0.694
HMPREF9018_0587
FtsK/SpoIIIE family protein (820 aa)
   
 
  0.667
HMPREF9018_1725
Ribonucleoside-diphosphate reductase ; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (839 aa)
   
   
  0.653
HMPREF9018_0701
Putative ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent (866 aa)
   
   
  0.653
HMPREF9018_1029
Peptidase, S41 family (525 aa)
   
   
  0.650
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 679191
Other names: P. amnii, P. amnii CRIS 21A-A, Prevotella amnii, Prevotella amnii CRIS 21A-A, Prevotella amnii Lawson et al. 2008, Prevotella amnii str. CRIS 21A-A, Prevotella amnii strain CRIS 21A-A
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