STRINGSTRING
der protein (Prevotella amnii) - STRING interaction network
"der" - GTP-binding protein EngA in Prevotella amnii
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
derGTP-binding protein EngA ; GTPase that plays an essential role in the late steps of ribosome biogenesis (437 aa)    
Predicted Functional Partners:
rplN
50S ribosomal protein L14 ; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (121 aa)
     
 
  0.986
rplA
50S ribosomal protein L1 ; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (230 aa)
 
 
  0.933
rplF
50S ribosomal protein L6 ; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center (188 aa)
   
 
  0.905
cmk
Cytidine monophosphate kinase (230 aa)
   
  0.894
rplX
50S ribosomal protein L24 ; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (105 aa)
   
 
  0.849
era
GTPase Era ; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (293 aa)
 
   
0.802
hflX
GTP-binding protein HflX ; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (418 aa)
   
  0.772
rplD
50S ribosomal protein L4 ; Forms part of the polypeptide exit tunnel (209 aa)
   
 
  0.772
HMPREF9018_0119
Uracil phosphoribosyltransferase (219 aa)
 
 
    0.721
HMPREF9018_1725
Ribonucleoside-diphosphate reductase ; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (839 aa)
   
 
  0.713
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 679191
Other names: P. amnii, P. amnii CRIS 21A-A, Prevotella amnii, Prevotella amnii CRIS 21A-A, Prevotella amnii Lawson et al. 2008, Prevotella amnii str. CRIS 21A-A, Prevotella amnii strain CRIS 21A-A
Server load: low (6%) [HD]