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folC protein (Prevotella amnii) - STRING interaction network
"folC" - Bifunctional protein FolC in Prevotella amnii
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
folCBifunctional protein FolC (436 aa)    
Predicted Functional Partners:
folP
Dihydropteroate synthase (270 aa)
 
  0.998
folD
Bifunctional protein FolD ; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (294 aa)
 
 
  0.991
folA
Dihydrofolate reductase ; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (161 aa)
   
  0.983
secD
Export membrane protein SecD ; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (1008 aa)
     
    0.901
glyA
Serine hydroxymethyltransferase ; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (426 aa)
   
  0.893
fhs
Formyltetrahydrofolate synthetase (555 aa)
   
 
  0.885
folK
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase (140 aa)
 
 
  0.879
folE
GTP cyclohydrolase I (195 aa)
 
 
  0.834
folB
7,8-dihydroneopterin aldolase ; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin (136 aa)
   
 
  0.831
thyA
Thymidylate synthase ; Provides the sole de novo source of dTMP for DNA biosynthesis (264 aa)
     
 
  0.827
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 679191
Other names: P. amnii, P. amnii CRIS 21A-A, Prevotella amnii, Prevotella amnii CRIS 21A-A, Prevotella amnii Lawson et al. 2008, Prevotella amnii str. CRIS 21A-A, Prevotella amnii strain CRIS 21A-A
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