STRINGSTRING
fhs protein (Prevotella amnii) - STRING interaction network
"fhs" - Formyltetrahydrofolate synthetase in Prevotella amnii
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
fhsFormyltetrahydrofolate synthetase (555 aa)    
Predicted Functional Partners:
folD
Bifunctional protein FolD ; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (294 aa)
 
  0.988
glyA
Serine hydroxymethyltransferase ; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (426 aa)
   
  0.919
HMPREF9018_1569
MGS-like domain protein (197 aa)
   
 
  0.911
HMPREF9018_0221
Phosphoribosylglycinamide synthetase (422 aa)
   
 
  0.895
HMPREF9018_0993
Uncharacterized protein (387 aa)
   
 
  0.894
purL
Formylglycinamide ribonucleotide amidotransferase ; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1247 aa)
   
   
  0.889
folC
Bifunctional protein FolC (436 aa)
   
 
  0.885
ftcD
Glutamate formimidoyltransferase (353 aa)
       
    0.870
HMPREF9018_1515
AICARFT/IMPCHase bienzyme (393 aa)
   
 
  0.868
folA
Dihydrofolate reductase ; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (161 aa)
   
 
  0.777
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 679191
Other names: P. amnii, P. amnii CRIS 21A-A, Prevotella amnii, Prevotella amnii CRIS 21A-A, Prevotella amnii Lawson et al. 2008, Prevotella amnii str. CRIS 21A-A, Prevotella amnii strain CRIS 21A-A
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