STRINGSTRING
dut protein (Prevotella amnii) - STRING interaction network
"dut" - Deoxyuridine 5'-triphosphate nucleotidohydrolase in Prevotella amnii
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
dutDeoxyuridine 5’-triphosphate nucleotidohydrolase ; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (173 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase ; Provides the sole de novo source of dTMP for DNA biosynthesis (264 aa)
   
  0.997
HMPREF9018_1725
Ribonucleoside-diphosphate reductase ; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (839 aa)
   
  0.993
HMPREF9018_0701
Putative ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent (866 aa)
   
  0.992
HMPREF9018_0788
Cytidine and deoxycytidylate deaminase zinc-binding region (145 aa)
   
 
    0.986
tadA
tRNA-specific adenosine deaminase ; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) (156 aa)
   
 
  0.981
nrdD
Anaerobic ribonucleoside-triphosphate reductase (698 aa)
       
  0.980
dnaN
DNA polymerase III subunit beta ; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (374 aa)
   
 
  0.973
HMPREF9018_1724
Ribonucleoside-diphosphate reductase subunit beta ; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (347 aa)
   
 
  0.953
HMPREF9018_0748
Deoxynucleoside kinase (204 aa)
     
 
    0.885
HMPREF9018_0747
Deoxynucleoside kinase (208 aa)
     
 
    0.885
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 679191
Other names: P. amnii, P. amnii CRIS 21A-A, Prevotella amnii, Prevotella amnii CRIS 21A-A, Prevotella amnii Lawson et al. 2008, Prevotella amnii str. CRIS 21A-A, Prevotella amnii strain CRIS 21A-A
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