STRINGSTRING
tgt protein (Prevotella amnii) - STRING interaction network
"tgt" - tRNA-guanine transglycosylase in Prevotella amnii
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tgttRNA-guanine transglycosylase ; Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (375 aa)    
Predicted Functional Partners:
HMPREF9018_0831
S-adenosylmethionine-tRNA ribosyltransferase-isomerase ; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (423 aa)
 
  0.998
HMPREF9018_0270
S-adenosylmethionine-tRNA ribosyltransferase-isomerase ; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (394 aa)
 
  0.997
queF
PreQ(0) reductase ; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (152 aa)
       
  0.986
lon
ATP-dependent protease La ; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (811 aa)
   
   
  0.891
HMPREF9018_1331
Permease, YjgP/YjgQ family (427 aa)
              0.877
secD
Export membrane protein SecD ; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (1008 aa)
   
   
  0.836
thyA
Thymidylate synthase ; Provides the sole de novo source of dTMP for DNA biosynthesis (264 aa)
 
   
  0.806
HMPREF9018_1330
DEAD/DEAH box helicase (567 aa)
   
      0.744
HMPREF9018_1334
tRNA m6A37 methyltransferase ; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (234 aa)
              0.729
HMPREF9018_1091
Peptidase M16 inactive domain protein (409 aa)
   
 
    0.682
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 679191
Other names: P. amnii, P. amnii CRIS 21A-A, Prevotella amnii, Prevotella amnii CRIS 21A-A, Prevotella amnii Lawson et al. 2008, Prevotella amnii str. CRIS 21A-A, Prevotella amnii strain CRIS 21A-A
Server load: low (9%) [HD]